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Lifestyle changes impacts on cardiovascular diseases: Brazil is in transition from malnutrition to obesity.
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Brasil. Ministério da Saúde. VIGITEL BRASIL 2016. Disponível em: https://www.endocrino.org.br/media/uploads/PDFs/vigitel.pdf. Acessado em: 20/04/2017.
The gut microbiome has been implicated in various metabolic and neurocognitive disorders and is heavily influenced by dietary factors. However, there is a paucity of research on the effects of added sugars on the gut microbiome.
In Experimental study, with aim was to determine how added-sugar consumption during the juvenile and adolescent phase of development affects the gut microbiome.
During the study, the animals were given access to 1 of 3 different carbohydrate solutions: 1) 35% fructose:65% glucose, 2) 50% fructose:50% glucose, 3) 65% fructose:35% glucose, and 4) control (no sugar).
Energy intake, weight change, and adiposity index were analyzed in relation to sugar consumption and the microbiota. Sugar consumption altered the gut microbiome independently of anthropometric measures and caloric intake.
At the genus level, Prevotella and Lachnospiraceae incertae sedis were reduced, whereas Bacteroides, Alistipes, Lactobacillus, Clostridium sensu stricto, Bifidobacteriaceae and Parasutterella were elevated by sugar consumption.
Ref: Noble EE, Hsu TM, Jones RB, Fodor AA, Goran MI, Kanoski SE. Early-Life Sugar Consumption Affects the Rat Microbiome Independently of Obesity. J Nutr. 2017;147(1):20-28.
A study published in the American Journal of Clinical Nutrition indicates a possible association between intake of sugar-sweetened beverages and obesity, moreover this association may be modified by a genetic predisposition to obesity.
Conducted by researchers at the Research Unit for Dietary Studies at the Parker Institute and Institute of Preventive Medicine in Denmark, the study assessed 4765 individuals. It was studied the interactions between genetic predisposition to obesity and soda consumption in relation to the annual variation in body weight, BMI, waist circumference (WC) and waist-hip ratio adjusted for BMI (WHR). The model for the assessment of genetic predisposition was built based on 50 single nucleotide polymorphisms associated with obesity, considering all these variables.
There was a significant mean increase of 0.07 kg / year each refrigerant portion ingested per day. “A genetic predisposition may strengthen the association between soft drink intake and BW”, the authors conclude.
Source: Olsen NJ, Angquist L, Larsen SC et al. Interactions between genetic variants associated with adiposity traits and soft drinks in relation to longitudinal changes in body weight and waist circunference. Am J Clin Nutr. 2016;27 [in press].